In laboratory animals, topical steroids have been associated with an increase in the incidence of fetal abnormalities when gestating females have been exposed to rather low dosage levels. As with other oral steroid drugs, the use of topical steroids should be considered with caution for pregnancy in young females. Furthermore, there is insufficient empirical data to support the use of topical steroids in pregnancy for treatment of benign prostatic hyperplasia, anabolic steroids a question of muscle. (See CONTRAINDICATIONS and WARNINGS.)Pregnancy Category CIn pregnant women, the risks and benefits of topical steroids are uncertain, however, their use in conjunction with other treatments is not contraindicated. (See CONTRAINDICATIONS, WARNINGS, PRECAUTIONS, and OVERDOSAGE, masteron dosage females for.)If clinical evidence is available showing that the presence of topical steroids in the vagina may contribute to abnormal findings or other indications for treatment, clinical trials may be necessary to determine the safest and most efficacious regimen for treatment of the condition.Clinical Trials (Safety, Tolerability, and Efficacy)Pregnancy Category CContraindicationsCarcinogenesis, Mutagenesis, Impairment of FertilityHIV infection, and other immune suppressing agents or the development of other immune-mediated diseases (see CONTRAINDICATIONS); andTobacco or alcohol use.Risk DiscussionNo serious adverse effects have been reported following topical treatment of the vaginal mucosa with steroids for the treatment of urogenital disorders (Table), legit steroid powder sources. In rats, administration of 3% nosalvonen or a topical steroid cream for 3 or 28 days in the postpartum period resulted in a dose-related reduction in urine production, which was associated with a decline in estrogen and progesterone (See Adverse Reactions and Pharmacokinetics).In vitro experiments suggest that a systemic exposure to topical steroids inhibits steroid hormone synthesis and can affect steroid hormone receptors, including ERα and ERβ, anabolic resistance exercise. A study in rabbits showed that systemic administration of Nosalvonen suppressed steroid hormone secretion by the testis but not by the ovary, which may be associated with an increase in testosterone, and in vivo studies showed no significant differences in the concentrations of urinary steroids between the active and a placebo group (see Adverse Reactions).The use of steroids in pregnancy with a view to the prevention or treatment of birth defects was not supported, dna laboratory testosteron erfahrungen.